Org 25969
SUGAMMADEX
CAS: 343306-71-8
Molecular Formula: C72H112O48S8
Org 25969 - Names and Identifiers
| Name | SUGAMMADEX |
| Synonyms | Bridion Org 25969 SUGAMMADEX Sugammagex Shu Glucose Unii-361lpm2T56 Sugammadex [inn] SugaMMadex SodiuM |
| CAS | 343306-71-8 |
| EINECS | 253-874-2 |
Org 25969 - Physico-chemical Properties
| Molecular Formula | C72H112O48S8 |
| Molar Mass | 2002.15 |
| Density | 1.559±0.06 g/cm3(Predicted) |
| Melting Point | >208°C (dec.) |
| Solubility | Aqueous Acid (Slightly), Water (Slightly, Sonicated) |
| Appearance | Solid |
| Color | White to Pale Beige |
| pKa | 3.42±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Stability | Hygroscopic |
Org 25969 - References
| muscle relaxant antagonist | , the US FDA approved the new drug Sugammadex (trade name Bridion) of the Netherlands Organon through the priority approval route. It is used to rapidly reverse the neuromuscular blockade caused by the anaesthetics rocuronium bromide and vecuronium bromide during surgery in adult patients. Sugengglucose is a synthetic Modified γ-cyclodextrin consisting of a lipophilic core and a hydrophilic outer end. Sugengglucose administered by intravenous injection can significantly improve the recovery of muscle relaxation after surgery, the rapid reversal of neuromuscular blockade by steroid muscle relaxants in a short period of time is of positive significance for improving the safety of general anesthesia. |
Last Update：2024-04-09 20:52:54
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View History
Org 25969
CIS-2-TERT-BUTOXYCARBONYLAMINO-CYCLOPENTANECARBOXYLIC ACID
1-氨基环丁烷羧酸乙酯盐酸盐
HOLMIUM-166M GAMMA-RAY EMISSION RATE STANDARD
反式对异丙基环己甲酸
D-苯基丙氨酸苄酯对甲苯磺酸盐
2-[(3-甲酰基噻吩-2-基)硫烷基]乙酸甲酯
CIS-2-TERT-BUTOXYCARBONYLAMINO-CYCLOPENTANECARBOXYLIC ACID
1-氨基环丁烷羧酸乙酯盐酸盐
HOLMIUM-166M GAMMA-RAY EMISSION RATE STANDARD
反式对异丙基环己甲酸
D-苯基丙氨酸苄酯对甲苯磺酸盐
2-[(3-甲酰基噻吩-2-基)硫烷基]乙酸甲酯